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Septrim: Medical Advice, Side Effects and Uses

Saddle 2d

View pictures in App save up to 80% data. Septrim, also known as Co-trimoxazole (a combination of Sulphamethoxazole and Trimethoprim) belong to the class of drugs known as sulphonamide antibiotics. It is formulated as tablets and paediatric syrup in Nigeria. Unfortunately, a lot of people abuse this drug because it is affordable and easily accessible. Some people use it to abort pregnancy because they claim it does so.

What is Co-trimoxazole Used for?

Co-trimoxazole is useful in treating various susceptible bacterial infections such as tonsilitis, acute bronchitis, sinusitus, cholera and typhoid (although not used again for this purpose because of antimicrobial resistance), etc. It is also used in the prophylaxis and treatment of opportunistic infections such as Pneumocystic carinii pneumonia (PCP) in people that have comprised immunity such as people that have HIV.

It is usually given at a dose of 25mg/kg for sulphamethoxazole and 5mg/kg for trimethoprim for both children and adults.

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What are the side effects of Septrim?

It can cause the following side effects:

  1. It can cause crystalluria which is essentially crystals in the urine, giving the urine a cloudy look. It can be very painful. This can be mitigated by drinking enough water when on this drug and other sulphonamide drugs such as Fansidar.
  2. Kidney stones
  3. Kernicterus in a newborn baby. This is a form of jaundice that can damage a baby's brain and organs.
  4. It can cause allergic or hypersensitivity reactions such as rashes, Stevens-Johnsons syndrome, toxic epidermal necrolysis, itching, exfoliative dermatitis, etc. This is to be reported to a healthcare practitioner such as the doctor or pharmacist and the drug must be discontinued with immediate effect.
  5. It may cause liver damage.
  6. It can cause aplastic anaemia and other associated blood disorders which requires that the drug is stopped.
  7. Nausea, Vomiting, diarrhoea, gastric upset and headache
  8. Antibiotic-associated colitis which is associated with diarrhoea and abdominal cramping.
  9. Tinnitus
  10. Electrolyte disturbances

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Medical Advice and Warning

  1. Ensure you used this with the advice of a physician or pharmacist. Tell them if you have experienced any form of drug reactions in the past as well. Also, report any form of side effects to them. Furthermore, discuss any medications you are taking with them.
  2. Take enough water and food with this drug.
  3. Don't use in pregnancy.
  4. Don't give to children less than 6 weeks old and in people with severe kidney and/or liver disease.

Always remember, all drugs are potential poisons

Till next time, stay healthy and safe.

Source: opera.com
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Top Comments
Saddle · 06/26/2020
Don't abuse Septrin please

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